ECATERINA MĂRIEȘ*, A.G. POPESCU***, D. POPESCU*,**^#

*Department of Physiology and Biophysics, Faculty of Biology, University of Bucharest, 91–95, Spl. Independenței, Bucharest, Romania
**Department of Mathematical Modeling in Life Sciences, Institute of Mathematical Statistics and Applied Mathematics of the Romanian Academy, 13, 13 Septembrie Street, 050911, Bucharest, Romania
***Department of Computer Sciences, IT CORE SRL, 10, Garoafei Street, 051235, Bucharest, Romania

In this paper, we have considered the problem of the pulsatory lipid vesicle which may be regarded as a two stroke engine using the osmotic solute as a fuel. The consumed fuel is usefulness material for neuromedical applications. It is known that the process leading to depression is the depletion of neurotransmitters in the synaptic cleft. This is designated as the biogenic amine theory of depression. So, a very interesting application of pulsatory liposomes may be the compensation of neurotransmitter deficiency into synaptic cleft. The pulsatory liposomes may be used as a device available for two from the four ways to compensate the neurotransmitter depletion by drug action: 1. to increase the release of neurotransmitters from the presynaptic terminal; 2. to delay the reuptake of neurotransmitters in the presynaptic neurons

Corresponding author’s e-mail: dghpopescu@gmail.com

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