N. CEAMITRU*, ILEANA ION*, CECILIA ADUMITRESI*, O. TEREN**, V. LUPESCU***

*Department of Physiology, **Department of Biophysics, ***Department of Orthopedic Surgery, Faculty of Medicine, “Ovidius” University, Constanţa, Romania

Abstract. In patients with limb fractures, in order to prevent venous thrombosis, before and after surgical intervention, anticoagulant substances are u administered. Because low molecular weight heparins (LMWH) derived from heparin by different depolymerization methods have a better bioavailability at low doses, they become the elective drugs in this treatment. In these cases, laboratory monitoring is not objective enough therefore, thrombelastography (Teg) has been reported as the best technique for monitoring heparinized patients. Our study was performed on two groups of hospitalized patients in orthopedic surgery and thrombelastogram was recorded before operation, immediately after it and seven days later. The differences between the groups consist in the different types of LMWH administered. Teg was able to emphasize the hypocoagulable status in patients under anticoagulant treatment even in the absence of the clinical signs.

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